Coach Tony Smith brings in Wigan half-back Sam Tomkins, Super League's young player of the year, in place of teenager Richie Myler, while Huddersfield front rower Eorl Crabtree takes the place of club-mate Scott Moore.
In positional changes from the team that beat France 34-12 at Doncaster last Friday, James Roby starts at hooker in place of Moore and skipper Jamie Peacock switches to the second row to accommodate prop James Graham in the starting line-up, with Sam Burgess dropping to the bench.
Myler missed the closing stages of the opening game through concussion but Smith said Tomkins, who scored a hat-trick of tries on debut against Wales, was always likely to get the nod this week.
"Richie has still got a bit of a head knock but Sam was going to get a chance this week," he told a press conference at the team's Manchester hotel.
"It gives us a chance to compare the two and decide which way we go for the final week.
"I've got lot of faith in both those young men but it's Sam's go this week."
England: S Briscoe (Hull KR); T Briscoe (Hull), Smith (Leeds), Shenton (Castleford), Hall (Leeds); McGuire (Leeds), Tomkins (Wigan); Morley (Warrington), Roby (St Helens), Graham (St Helens), Ellis (Wests Tigers), Peacock (Leeds, captain), Sinfield (Leeds).
Substitutes: Burgess (Bradford), Crabtree (Huddersfield), Eastmond (St Helens), Westwood (Warrington).
Tickets for Saturday's Gillette Four Nations game between England and Australia at DW Stadium, Wigan (2.30 kick-off) are still available and prices start from £20.
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